Latest X update crashes aMule-20070927-0.pm.1 similar to:

Initialising aMule 
 Checking if there is an instance already running... 
 No other instances are running. 
 The program 'amule' received an X Window System error. 
 This probably reflects a bug in the program. 
 The error was 'BadAlloc (insufficient resources for operation)'. 
 (Details: serial 650 error_code 11 request_code 147 minor_code 5) 
 (Note to programmers: normally, X errors are reported asynchronously; 
  that is, you will receive the error a while after causing it. 
 To debug your program, run it with the --sync command line 
 option to change this behavior. You can then get a meaningful 
 backtrace from your debugger if you break on the gdk_x_error() function.) 

Looks like it happens for 10.3 also:
http://www.linux-club.de/ftopic90337.html